

The burden and progressive deterioration of these diseases depend mostly on the occurrence of exacerbations, causing frequent unscheduled medical visits, emergency department visits and hospitalizations. The main impact and cause of death in CF is respiratory failure associated with chronic and recurrent infections, and its overall cost tends to grow as the disease progresses. Cystic fibrosis (CF) has an incidence of 70,000 to 100,000 people worldwide and affects more and more the adult population. The overall burden and direct and indirect cost of uncontrolled asthma are high. Asthma affects about 339 million people and represents one of the most common chronic pediatric diseases.

Respiratory diseases are a major public health problem, with a growing burden to healthcare systems and to society. Our results show that smartphone auscultation was feasible, but further investigation is required to improve its agreement with conventional auscultation. Adventitious sounds were present in only 35% of the participants and 14% of the recordings, which may have contributed to the fair agreement between conventional and smartphone auscultation (85% k = 0.35(95% CI 0.26–0.44)). Seventy-three percent of recordings had quality (obtained in 92% of the participants), with the quality proportion being higher at the trachea (82%) and in the children’s group (75%). The recordings (n = 1060) were classified by two annotators. Then, smartphone auscultation was recorded twice in the same four locations. First, clinicians performed conventional auscultation with analog stethoscopes at 4 locations (trachea, right anterior chest, right and left lung bases), and documented any adventitious sounds. We recruited 134 patients (median 16y 54% male 31% cystic fibrosis, 29% other respiratory diseases, 28% asthma 12% no respiratory diseases) at the Pediatrics and Pulmonology departments of a tertiary hospital. We assessed the feasibility of lung auscultation using the smartphone built-in microphone in real-world clinical practice. However, detecting adventitious sounds outside medical facilities remains challenging. Conventional lung auscultation is essential in the management of respiratory diseases.
